Endocrine System - AP Biology

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Question

Amy has osteoporosis, which is a disease that affects the bone. It occurs in individuals with low calcium levels in their bones. The bones become weak, brittle and may break. Which of the following hormones would she need to produce to help reduce the problems associated with osteoporosis?

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Answer

Calcitonin is the hormone in charge of taking calcium ions from the bloodstream and incorporating them into the matrix of the bone. This allows the bone to produce hydroxyapatite crystals from the calcium, which can strengthen the matrix of the bone and reduce the effect of osteoporosis. Parathyroid hormone and calcitriol (vitamin D) have opposite effects as calcitonin - they increase the blood calcium levels through breaking down bone and increasing the absorption of calcium in the gut. Growth hormone is responsible for normal growth and development of the body, especially bones and skeletal muscles. It is not involved in regulation of minerals such as calcium. Calmodulin is a calcium binding protein that regulates many intracellular processes.

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